An amazing list of words that Shakespeare used first, by Amanda Mabillard:

academe accused addiction advertising amazement arouse assassination backing bandit bedroom beached besmirch birthplace blanket bloodstained barefaced blushing bet bump buzzer caked cater champion circumstantial cold-blooded compromise courtship countless critic dauntless dawn deafening discontent dishearten drugged dwindle epileptic equivocal elbow excitement exposure eyeball fashionable fixture flawed frugal generous gloomy gnarled gossip green-eyed grovel gust hint hobnob hurried impede impartial invulnerable jaded label lackluster laughable lonely lower luggage lustrous madcap majestic marketable metamorphize mimic monumental moonbeam mountaineer negotiate noiseless obscene obsequiously ode olympian outbreak panders pedant premeditated puking radiance rant remorseless savagery scuffle secure skim milk submerge summit swagger torture tranquil undress unreal varied vaulting worthless zany

(cf. WillInTheWorld (2005-04-20), Bryson on Shakespeare (2010-06-21), ...) - ^z - 2013-01-31